The Ras superfamily at a glance.

The Ras protein superfamily: Evolutionary tree and role of conserved amino acids

The Ras superfamily is a fascinating example of functional diversification in the context of a preserved structural framework and a prototypic GTP binding site. Thanks to the availability of complete genome sequences of species representing important evolutionary branch points, we have analyzed the composition and organization of this superfamily at a greater level than was previously possible....

RAS isoforms and mutations in cancer at a glance.

RAS proteins (KRAS4A, KRAS4B, NRAS and HRAS) function as GDP-GTP-regulated binary on-off switches, which regulate cytoplasmic signaling networks that control diverse normal cellular processes. Gain-of-function missense mutations in RAS genes are found in ∼25% of human cancers, prompting interest in identifying anti-RAS therapeutic strategies for cancer treatment. However, despite more than thre...

ProtFract: A server to calculate interior and exterior fractal properties of proteins

Motivation: Protein surface roughness is fractal in nature. Mass, hydrophobicity, polarizability distributions of protein interior are fractal too, as are the distributions of dipole moments, aromatic residues, and many other structural determinants. The open-access server ProtFract, presents a reliable way to obtain numerous fractaldimension and correlation-dimension based results to quantify ...

The University of Social Welfare and Rehabilitation Sciences at a Glance

A Glance at Psychophysics Software Programs

Visual stimulation with precise control of stimulus has transformed the field of psychophysics since the introduction of personal computers. Luminance and chromatic features of stimulus, timing, and position of the stimulus are the main features that could be defined using programs written specifically for psychophysical experiments. In this manuscript, software used for the psychophysical expe...